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Articles (90)
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Traditional Medicine Collection Tracking System (TM-CTS): A database for ethnobotanically driven drug-discovery programs

Eric S.J. Harris, Sean D. Erickson, Andrew N. Tolopko, Shugeng Cao, Jane A. Craycroft, Robert Scholten, Yanling Fu, Wenquan Wang, Yong Liu, Zhongzhen Zhao, Jon Clardy, Caroline E. Shamu, David M. Eise

Journal:

Journal of Ethnopharmacology

Année:

2011

Langue:

english

Fichier:

PDF, 462 KB

english, 2011

Current Protocols in Chemical Biology || Evolving Aptamers with Unnatural Base Pairs

Mahal, Lara, Romesberg, Floyd, Shah, Kavita, Shamu, Caroline, Strano, Michael S., Thomas, Craig

Année:

2009

Langue:

english

Fichier:

PDF, 1.74 MB

english, 2009

RNAi screening comes of age: improved techniques and complementary approaches

Mohr, Stephanie E., Smith, Jennifer A., Shamu, Caroline E., Neumüller, Ralph A., Perrimon, Norbert

Journal:

Nature Reviews Molecular Cell Biology

Année:

2014

Langue:

english

Fichier:

PDF, 923 KB

english, 2014

Current Protocols in Chemical Biology || Fluorescence Polarization (FP) Assays for Monitoring Peptide-Protein or Nucleic Acid-Protein Binding

Arkin, Adam P., Mahal, Lara, Romesberg, Floyd, Shah, Kavita, Shamu, Caroline, Thomas, Craig

Année:

2009

Langue:

english

Fichier:

PDF, 143 KB

english, 2009

Current Protocols in Chemical Biology || Copper-Catalyzed Azide-Alkyne Click Chemistry for Bioconjugation

Arkin, Adam P., Mahal, Lara, Romesberg, Floyd, Shah, Kavita, Shamu, Caroline, Thomas, Craig

Année:

2009

Langue:

english

Fichier:

PDF, 144 KB

english, 2009

Current Protocols in Chemical Biology || Enriching s 4 U-RNA Using Methane Thiosulfonate (MTS) Chemistry

Mahal, Lara, Romesberg, Floyd, Shah, Kavita, Shamu, Caroline, Strano, Michael S., Thomas, Craig

Année:

2009

Langue:

english

Fichier:

PDF, 368 KB

english, 2009

C. elegans unc-4 gene encodes a homeodomain protein that determines the pattern of synaptic input to specific motor neurons

Miller, David M., Shen, Michael M., Shamu, Caroline E., Bürglin, Thomas R., Ruvkun, Gary, Dubois, Michelle L., Ghee, Medeva, Wilson, Laura

Journal:

Nature

Année:

1992

Fichier:

PDF, 601 KB

1992

10.1038/35618

Zarkower, David, Raymond, Christopher S., Shamu, Caroline E., Shen, Michael M., Seifert, Kelly J., Hirsch, Betsy, Hodgkin, Jonathan

Journal:

Nature

Année:

1998

Langue:

english

Fichier:

PDF, 404 KB

english, 1998

Reporting data from high-throughput screening of small-molecule libraries

Inglese, James, Shamu, Caroline E, Guy, R Kiplin

Journal:

Nature Chemical Biology

Année:

2007

Langue:

english

Fichier:

PDF, 1.50 MB

english, 2007

The unfolded-protein-response pathway in yeast

Caroline E. Shamu, Jeffery S. Cox, Peter Walter

Journal:

Trends in Cell Biology

Année:

1994

Langue:

english

Fichier:

PDF, 685 KB

english, 1994

Measure, mine, model, and manipulate: the future for HTS and chemoinformatics?

Christian N. Parker, Caroline E. Shamu, Brian Kraybill, Christopher P. Austin, Jürgen Bajorath

Journal:

Drug Discovery Today

Année:

2006

Langue:

english

Fichier:

PDF, 92 KB

english, 2006

Signal transduction: Splicing together the unfolded-protein response

Caroline E Shamu

Journal:

Current Biology

Année:

1997

Langue:

english

Fichier:

PDF, 240 KB

english, 1997

Splicing: HACking into the unfolded-protein response

Caroline E Shamu

Journal:

Current Biology

Année:

1998

Langue:

english

Fichier:

PDF, 221 KB

english, 1998

For nascent researchers: At the Bench: A Laboratory Navigator by Kathy Barker

Caroline E. Shamu

Journal:

Trends in Cell Biology

Année:

1999

Langue:

english

Fichier:

PDF, 34 KB

english, 1999

Current Protocols in Chemical Biology Volume 453 || In Situ Hybridization Assay-Based Small-Molecule Screening in Zebrafish

Arkin, Adam P., Mahal, Lara, Romesberg, Floyd, Shah, Kavita, Shamu, Caroline, Thomas, Craig

Année:

2009

Langue:

english

Fichier:

PDF, 297 KB

english, 2009

Degradation of Proteins from the ER of S. cerevisiae Requires an Intact Unfolded Protein Response Pathway

Rocco Casagrande, Patrick Stern, Maximilian Diehn, Caroline Shamu, Manuel Osario, Martha Zúñiga, Patrick O Brown, Hidde Ploegh

Journal:

Molecular Cell

Année:

2000

Langue:

english

Fichier:

PDF, 178 KB

english, 2000

Screensaver: an open source lab information management system (LIMS) for high throughput screening facilities

Andrew N Tolopko, John P Sullivan, Sean D Erickson, David Wrobel, Su L Chiang, Katrina Rudnicki, Stewart Rudnicki, Jennifer Nale, Laura M Selfors, Dara Greenhouse, Jeremy L Muhlich, Caroline E Shamu

Journal:

BMC Bioinformatics

Année:

2010

Langue:

english

Fichier:

PDF, 10.22 MB

english, 2010

Transcriptional induction of genes encoding endoplasmic reticulum resident proteins requires a transmembrane protein kinase

Jeffery S. Cox, Caroline E. Shamu, Peter Walter

Journal:

Cell

Année:

1993

Langue:

english

Fichier:

PDF, 1.84 MB

english, 1993

Current Protocols in Chemical Biology || A Screening Protocol for Identification of Functional Mutants of RNA Editing Adenosine Deaminases

Arkin, Adam P., Mahal, Lara, Romesberg, Floyd, Shah, Kavita, Shamu, Caroline, Thomas, Craig

Année:

2009

Langue:

english

Fichier:

PDF, 338 KB

english, 2009

Current Protocols in Chemical Biology || Selecting, Acquiring, and Using Small Molecule Libraries for High-Throughput Screening

Arkin, Adam P., Mahal, Lara, Romesberg, Floyd, Shah, Kavita, Shamu, Caroline, Thomas, Craig

Année:

2009

Langue:

english

Fichier:

PDF, 214 KB

english, 2009

Current Protocols in Chemical Biology || In Vivo Imaging and Biochemical Characterization of Protease Function Using Fluorescent Activity-Based Probes

Arkin, Adam P., Mahal, Lara, Romesberg, Floyd, Shah, Kavita, Shamu, Caroline, Thomas, Craig

Année:

2009

Langue:

english

Fichier:

PDF, 316 KB

english, 2009

Current Protocols in Chemical Biology || Bioorthogonal Chemical Reporters for Analyzing Protein Sulfenylation in Cells

Arkin, Adam P., Mahal, Lara, Romesberg, Floyd, Shah, Kavita, Shamu, Caroline, Thomas, Craig

Année:

2009

Langue:

english

Fichier:

PDF, 623 KB

english, 2009

Current Protocols in Chemical Biology || A High-Throughput Screening Method for Identification of Inhibitors of the Deubiquitinating Enzyme USP14

Arkin, Adam P., Mahal, Lara, Romesberg, Floyd, Shah, Kavita, Shamu, Caroline, Thomas, Craig

Année:

2009

Langue:

english

Fichier:

PDF, 510 KB

english, 2009

Current Protocols in Chemical Biology || High-Throughput Assessment of Bacterial Growth Inhibition by Optical Density Measurements

Arkin, Adam P., Mahal, Lara, Romesberg, Floyd, Shah, Kavita, Shamu, Caroline, Thomas, Craig

Année:

2009

Langue:

english

Fichier:

PDF, 230 KB

english, 2009

Current Protocols in Chemical Biology || Spatiotemporal Control of Gene Expression in Mammalian Cells and in Mice Using the LightOn System

Arkin, Adam P., Mahal, Lara, Romesberg, Floyd, Shah, Kavita, Shamu, Caroline, Thomas, Craig

Année:

2009

Langue:

english

Fichier:

PDF, 735 KB

english, 2009

Current Protocols in Chemical Biology || Compound Management: Guidelines for Compound Storage, Provision, and Quality Control

Arkin, Adam P., Mahal, Lara, Romesberg, Floyd, Shah, Kavita, Shamu, Caroline, Thomas, Craig

Année:

2009

Langue:

english

Fichier:

PDF, 556 KB

english, 2009

Current Protocols in Chemical Biology || Targeted Degradation of Proteins by PROTACs

Arkin, Adam P., Mahal, Lara, Romesberg, Floyd, Shah, Kavita, Shamu, Caroline, Thomas, Craig

Année:

2009

Langue:

english

Fichier:

PDF, 862 KB

english, 2009

Current Protocols in Chemical Biology || Chemical Genetic Approach for Kinase-Substrate Mapping by Covalent Capture of Thiophosphopeptides and Analysis by Mass Spectrometry

Arkin, Adam P., Mahal, Lara, Romesberg, Floyd, Shah, Kavita, Shamu, Caroline, Thomas, Craig

Année:

2009

Langue:

english

Fichier:

PDF, 397 KB

english, 2009

Current Protocols in Chemical Biology || Measurement of Protein Phosphorylation Stoichiometry by SRM-MS

Arkin, Adam P., Mahal, Lara, Romesberg, Floyd, Shah, Kavita, Shamu, Caroline, Thomas, Craig

Année:

2009

Langue:

english

Fichier:

PDF, 463 KB

english, 2009

The Pathway of US11-Dependent Degradation of MHC Class I Heavy Chains Involves a Ubiquitin-Conjugated Intermediate

Caroline E. Shamu, Craig M. Story, Tom A. Rapoport and Hidde L. Ploegh

Journal:

The Journal of Cell Biology

Année:

1999

Langue:

english

Fichier:

PDF, 3.83 MB

english, 1999

Sister Chromatid Separation in Frog Egg Extracts Requires DNA Topoisomerase II Activity during Anaphase

Caroline E. Shamu and Andrew W. Murray

Journal:

The Journal of Cell Biology

Année:

1992

Langue:

english

Fichier:

PDF, 2.83 MB

english, 1992

Current Protocols in Chemical Biology || Manipulating Natural Product Biosynthetic Pathways via DNA Assembler

Mahal, Lara, Romesberg, Floyd, Shah, Kavita, Shamu, Caroline, Strano, Michael S., Thomas, Craig

Année:

2009

Langue:

english

Fichier:

PDF, 892 KB

english, 2009

Current Protocols in Chemical Biology || Kinase-Catalyzed Biotinylation of Peptides, Proteins, and Lysates

Arkin, Adam P., Mahal, Lara, Romesberg, Floyd, Shah, Kavita, Shamu, Caroline, Thomas, Craig

Année:

2009

Langue:

english

Fichier:

PDF, 345 KB

english, 2009

Current Protocols in Chemical Biology || Gene Assembly from Chip-Synthesized Oligonucleotides

Arkin, Adam P., Mahal, Lara, Romesberg, Floyd, Shah, Kavita, Shamu, Caroline, Thomas, Craig

Année:

2009

Langue:

english

Fichier:

PDF, 241 KB

english, 2009

Current Protocols in Chemical Biology || Chemoenzymatic Site-Specific Reversible Immobilization and Labeling of Proteins from Crude Cellular Extract Without Prior Purification Using Oxime and Hydrazine Ligation

Arkin, Adam P., Mahal, Lara, Romesberg, Floyd, Shah, Kavita, Shamu, Caroline, Thomas, Craig

Année:

2009

Langue:

english

Fichier:

PDF, 950 KB

english, 2009

Current Protocols in Chemical Biology || Site-Specific Protein Bioconjugation via a Pyridoxal 5′-Phosphate-Mediated N-Terminal Transamination Reaction

Arkin, Adam P., Mahal, Lara, Romesberg, Floyd, Shah, Kavita, Shamu, Caroline, Thomas, Craig

Année:

2009

Langue:

english

Fichier:

PDF, 210 KB

english, 2009

Current Protocols in Chemical Biology || High-Throughput Screening for Novel Anti-Infectives Using a C. elegans Pathogenesis Model

Mahal, Lara, Romesberg, Floyd, Shah, Kavita, Shamu, Caroline, Strano, Michael S., Thomas, Craig

Année:

2009

Langue:

english

Fichier:

PDF, 459 KB

english, 2009

A High-Throughput, Cell-Based Screening Method for siRNA and Small Molecule Inhibitors of mTORC1 Signaling Using the In Cell Western Technique

Hoffman, Gregory R., Moerke, Nathan J., Hsia, Max, Shamu, Caroline E., Blenis, John

Journal:

Assay and Drug Development Technologies

Année:

2010

Langue:

english

Fichier:

PDF, 6.22 MB

english, 2010

Current Protocols in Chemical Biology || SHAPE-Seq: High-Throughput RNA Structure Analysis

Arkin, Adam P., Mahal, Lara, Romesberg, Floyd, Shah, Kavita, Shamu, Caroline, Thomas, Craig

Année:

2009

Langue:

english

Fichier:

PDF, 902 KB

english, 2009

Current Protocols in Chemical Biology || Triple-Addition Assay Protocols for Detecting and Characterizing Modulators of Seven-Transmembrane Receptors

Arkin, Adam P., Mahal, Lara, Romesberg, Floyd, Shah, Kavita, Shamu, Caroline, Thomas, Craig

Année:

2009

Langue:

english

Fichier:

PDF, 348 KB

english, 2009

Current Protocols in Chemical Biology || Glycomic Analysis of Glycans Released from Glycoproteins Using Chemical Immobilization and Mass Spectrometry

Mahal, Lara, Romesberg, Floyd, Shah, Kavita, Shamu, Caroline, Strano, Michael S., Thomas, Craig

Année:

2009

Langue:

english

Fichier:

PDF, 1.09 MB

english, 2009

Current Protocols in Chemical Biology || Bioorthogonal Profiling of Protein Methylation (BPPM) Using an Azido Analog of S -Adenosyl- L -Methionine

Arkin, Adam P., Mahal, Lara, Romesberg, Floyd, Shah, Kavita, Shamu, Caroline, Thomas, Craig

Année:

2009

Langue:

english

Fichier:

PDF, 368 KB

english, 2009

Current Protocols in Chemical Biology || Analyzing In Vivo Metabolite-Protein Interactions by Large-Scale Systematic Analyses

Arkin, Adam P., Mahal, Lara, Romesberg, Floyd, Shah, Kavita, Shamu, Caroline, Thomas, Craig

Année:

2009

Langue:

english

Fichier:

PDF, 302 KB

english, 2009

Current Protocols in Chemical Biology || Target Identification by Diazirine Photo-Cross-Linking and Click Chemistry

Arkin, Adam P., Mahal, Lara, Romesberg, Floyd, Shah, Kavita, Shamu, Caroline, Thomas, Craig

Année:

2009

Langue:

english

Fichier:

PDF, 557 KB

english, 2009

On target: A public repository for large-scale RNAi experiments

Shamu, Caroline E., Wiemann, Stefan, Boutros, Michael

Journal:

Nature Cell Biology

Année:

2012

Langue:

english

Fichier:

PDF, 91 KB

english, 2012

Current Protocols in Chemical Biology || Nanolithography Based on Metalized DNA Templates for Graphene Patterning

Mahal, Lara, Romesberg, Floyd, Shah, Kavita, Shamu, Caroline, Strano, Michael S., Thomas, Craig

Année:

2009

Langue:

english

Fichier:

PDF, 854 KB

english, 2009

Current Protocols in Chemical Biology || Visualization of O -GlcNAc Glycosylation Stoichiometry and Dynamics Using Resolvable Poly(ethylene glycol) Mass Tags

Mahal, Lara, Romesberg, Floyd, Shah, Kavita, Shamu, Caroline, Strano, Michael S., Thomas, Craig

Année:

2009

Langue:

english

Fichier:

PDF, 660 KB

english, 2009

Current Protocols in Chemical Biology || Chemical Synthesis of Hydrocarbon-Stapled Peptides for Protein Interaction Research and Therapeutic Targeting

Arkin, Adam P., Mahal, Lara, Romesberg, Floyd, Shah, Kavita, Shamu, Caroline, Thomas, Craig

Année:

2009

Langue:

english

Fichier:

PDF, 325 KB

english, 2009

Current Protocols in Chemical Biology || Target Identification Using Drug Affinity Responsive Target Stability (DARTS)

Arkin, Adam P., Mahal, Lara, Romesberg, Floyd, Shah, Kavita, Shamu, Caroline, Thomas, Craig

Année:

2009

Langue:

english

Fichier:

PDF, 243 KB

english, 2009

Current Protocols in Chemical Biology || Evaluation of Compounds in Primary Human Islet Cell Culture

Mahal, Lara, Romesberg, Floyd, Shah, Kavita, Shamu, Caroline, Strano, Michael S., Thomas, Craig

Année:

2009

Langue:

english

Fichier:

PDF, 400 KB

english, 2009